| Autor: |
Kunesch N; Laboratoire de Chimie des Substances thérapeutiques naturelles, UA CNRS n. 496, Centre d'Etudes pharmaceutiques, Châtenay-Malabry., Barbier MP, Dalkafouki A, Poisson JE |
| Jazyk: |
francouzština |
| Zdroj: |
Annales pharmaceutiques francaises [Ann Pharm Fr] 1990; Vol. 48 (1), pp. 1-6. |
| Abstrakt: |
Several new derivatives of the aldehydic functions of (+/-) gossypol are described: an hydrosoluble hydrazide resulting from the reaction with the Girard's reagent T and Schiff bases with polyamines. The condensation between the two aldehyde groups and cadaverine, putrescine or spermidine gives macrocyclic bridged products. A disubstituted non cyclic derivative is obtained with an excess of cadaverine. These products are of biological interest. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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