Phenolic dimers and an indole alkaloid from Campylospermum flavum (Ochnaceae).
| Autor: | Ndongo JT; Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon., Shaaban M, Mbing JN, Bikobo DN, Atchadé Ade T, Pegnyemb DE, Laatsch H |
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| Jazyk: | angličtina |
| Zdroj: | Phytochemistry [Phytochemistry] 2010 Nov; Vol. 71 (16), pp. 1872-8. Date of Electronic Publication: 2010 Sep 06. |
| DOI: | 10.1016/j.phytochem.2010.08.006 |
| Abstrakt: | From the leaves and stem bark of Campylospermum flavum (Ochnaceae), three compounds, namely 4‴-O-methylagathisflavone, flavumchalcone, and flavumindole have been isolated together with 10 known compounds, including three flavonoids, two biflavonoids, two alkaloids, two nitrile glucosides, and glucopyranosyl-β-sistosterol. The structures of these compounds and their relative configurations were established by 1D and 2D NMR experiments. The methanolic crude extracts of leaves and stem bark of C. flavum and compounds displayed a significant cytotoxicity towards Artemia salina larvae. (Copyright © 2010 Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
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