Oxidative stress in obstructive nephropathy.
| Autor: | Dendooven A; Department of Pathology, University Medical Center, Utrecht, The Netherlands., Ishola DA Jr, Nguyen TQ, Van der Giezen DM, Kok RJ, Goldschmeding R, Joles JA |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | International journal of experimental pathology [Int J Exp Pathol] 2011 Jun; Vol. 92 (3), pp. 202-10. Date of Electronic Publication: 2010 Aug 27. |
| DOI: | 10.1111/j.1365-2613.2010.00730.x |
| Abstrakt: | Unilateral ureteric obstruction (UUO) is one of the most commonly applied rodent models to study the pathophysiology of renal fibrosis. This model reflects important aspects of inflammation and fibrosis that are prominent in human kidney diseases. In this review, we present an overview of the factors contributing to the pathophysiology of UUO, highlighting the role of oxidative stress. (© 2010 The Authors. International Journal of Experimental Pathology © 2010 International Journal of Experimental Pathology.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|