Epoprostenol treatment for idiopathic pulmonary arterial hypertension in pregnancy.

Autor: Garabedian MJ; Department of Obstetrics and Gynecology, University of Kentucky, Lexington, KY, USA. matt.garabedian@uky.edu, Hansen WF, Gianferrari EA, Lain KY, Fragneto RY, Campbell CL, Booth DC
Jazyk: angličtina
Zdroj: Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2010 Sep; Vol. 30 (9), pp. 628-31.
DOI: 10.1038/jp.2010.15
Abstrakt: Idiopathic pulmonary arterial hypertension is a rare condition associated with significant maternal mortality. We report the management of a 37-year-old multigravida with severe disease using epoprostenol, a multidisciplinary approach, and a planned delivery. Although the patient survived the pregnancy, her pulmonary function significantly worsened. Epoprostenol, a pulmonary vasodilator, should be considered when indicated during pregnancy. Neither fetal nor neonatal harm was identified.
Databáze: MEDLINE