Intestinal schwannoma in a rhesus monkey.

Autor: Barbolt TA; Toxicology Department, Sterling Research Group, Rensselaer, NY 12144., Egy MA
Jazyk: angličtina
Zdroj: Journal of comparative pathology [J Comp Pathol] 1990 Nov; Vol. 103 (4), pp. 471-5.
DOI: 10.1016/s0021-9975(08)80035-7
Abstrakt: An intestinal schwannoma (neurilemmoma) was found in an aged female rhesus monkey culled from a research colony. The neoplasm was characterized principally by palisades of spindle-shaped cells (Antoni type A) surrounded by thick argyrophilic fibres, while plump cells with areas of vacuolation (Antoni type B) were observed to a lesser extent. Thick hyalinized perivascular cuffs were prominent and multifocal thromboses were present in cavernous vascular channels. Electron microscopic examination of the intercellular matrix between Antoni type A cells revealed long-spacing (100 to 120 nm) collagen fibrils. Although the mass had expanded beyond the confines of the muscularis externa, the cytological features of the neoplasm appeared benign.
Databáze: MEDLINE