[Specific antibodies in children with recurrent respiratory infections immunized with pneumo 23 and Act-HIB vaccines].

Autor: Foshina EP, Kostinov MP, Iastrebova NE
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2010 Jul-Aug (4), pp. 37-40.
Abstrakt: Aim: Assessment of specific IgG levels in children with recurrent respiratory infections after immunization with Pneumo 23 and Act-HIB vaccines.
Materials and Methods: Concentrations of IgG to polysaccharide capsular antigens and cell wall antigens of Streptococcus pneumoniae and Haemophilus influenzae were measured by solid-phase ELISA in sera of 256 immunized children.
Results: Increase of levels of IgG to cell wall antigens and certain polysaccharide antigens was observed in patients with low or intermediate antibody levels at baseline.
Conclusion: Obtained results allow to conclude that vaccination of children with recurrent respiratory and middle ear infections results in induction of IgG production that proves immunological effect of performed vaccination.
Databáze: MEDLINE