[The hygienic validation of the MPEL for the fungicide tekto in reservoir water].

Autor: Kedrova II, Balakireva SI, Kremko LM, Levoshuk NP, Kagan NA, Karaseva AE, Petrovich IN
Jazyk: ruština
Zdroj: Gigiena i sanitariia [Gig Sanit] 1990 Oct (10), pp. 28-30.
Abstrakt: Fungicide tecto (thiabendazol) is a low-toxic compound, produces a weak skin-resorptive and local irritating effect. Cumulation coefficient is 3.96. Threshold and subthreshold doses for tecto were determined as a result of 12-months chronic experiment on white rats--3.7 and 0.37 mg/kg, respectively. The allowable 24-hours dose for human exposure to the chemical is 0.6 mg. The threshold tecto concentration according to the effect on the general sanitary regimen of water reservoirs appeared to be 1 mg/l. According to the limiting toxicological index 0.05 mg/l was recommended as tecto MAC for the water of reservoirs.
Databáze: MEDLINE