Microbial adhesion to surface-grafted polyacrylamide brushes after long-term exposure to PBS and reconstituted freeze-dried saliva.

Autor: Fundeanu I; Department of Polymer Chemistry, Zernike Institute of Advanced Materials, University of Groningen, Groningen, The Netherlands., van der Mei HC, Schouten AJ, Busscher HJ
Jazyk: angličtina
Zdroj: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2010 Sep 01; Vol. 94 (3), pp. 997-1000.
DOI: 10.1002/jbm.a.32789
Abstrakt: Polyacrylamide (PAAm) brushes, covalently grafted from silicon wafer surfaces were examined for their ability to inhibit microbial adhesion after long-term exposure to PBS or reconstituted freeze-dried saliva for time intervals from 48 h up to 1 month at 37 degrees C. Microbial adhesion after exposure was studied in a parallel plate flow chamber. Infrared spectra showed that PAAm brushes exhibit good chemical stability upon incubation in both PBS and reconstituted freeze-dried saliva up to 1 month. Reductions in microbial adhesion on PAAm brushes after exposure to PBS or reconstituted freeze-dried saliva varied from 63 to 93% depending on the microbial strain considered, even after 1 month of exposure of the brushes to reconstituted freeze-dried saliva.
((c) 2010 Wiley Periodicals, Inc.)
Databáze: MEDLINE
Externí odkaz: