| Autor: |
Verweij WR; Department of Medical Microbiology, School of Medicine, Vrije Universiteit, Amsterdam, The Netherlands., Namavar F, Schouten WF, MacLaren DM |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of medical microbiology [J Med Microbiol] 1991 Jul; Vol. 35 (1), pp. 18-22. |
| DOI: |
10.1099/00222615-35-1-18 |
| Abstrakt: |
Growth of Bacteroides fragilis and Escherichia coli was monitored during early stages of single (mono-) and mixed intra-abdominal infection in a rat fibrin clot model. When B. fragilis and E. coli were together involved in the infection, B. fragilis numbers increased about 6 h after an initial decline. This increase was not found with B. fragilis mono-infections. The numbers of E. coli increased rapidly in both mono- and mixed infections and stayed high for several days, but only mixed infection resulted in abscesses that persisted for more than 7 days. Macrophages, the main component of the peritoneal cellular defence mechanism, were outnumbered by polymorphonuclear leucocytes during the first 6 h of infection. Further characterisation of the macrophage population by means of monoclonal antibodies showed a shift from resident to exudate macrophages as the result of influx of the latter. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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