Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.

Autor: Goldberg AA; Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada., Kyryakov P, Bourque SD, Titorenko VI
Jazyk: angličtina
Zdroj: Aging [Aging (Albany NY)] 2010 Aug; Vol. 2 (8), pp. 461-70.
DOI: 10.18632/aging.100186
Abstrakt: We recently found that lithocholic acid (LCA), a bile acid, extends yeast longevity. Unlike mammals, yeast do not synthesize bile acids. We therefore propose that bile acids released into the environment by mammals may act as interspecies chemical signals providing longevity benefits to yeast and, perhaps, other species within an ecosystem.
Databáze: MEDLINE