Surgical technique in cadaveric donors for partial hand allotransplant in patients with rheumatoid arthritis.

Autor: Iglesias M; Plastic Surgery Service, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico Distrito Federal, Mexico. martiniglesiasm@gmail.com, Butrón P, Santander-Flores S, Ricaño-Enciso D, Negrete-Najar JP, Pérez-Monzó MF, González-Chávez A, González-Chávez M, de Rienzo-Madero B, Hamdan-Pérez N
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2010 Jul-Aug; Vol. 42 (6), pp. 2389-94.
DOI: 10.1016/j.transproceed.2010.05.001
Abstrakt: For patients with severe hand deformities due to rheumatoid arthritis, we propose an allotransplantation of an osteomyotendinose structure (OMTS), preserving the recipient's skin and sensory nerves. Our objective was to develop the surgical technique in a 10 cadavers, five as donors and five as recipients. The donor's hand was 10% to 15% smaller than the recipient's. Dissections were performed by two surgical teams under magnification. In the donor, the OMTS was procured at the distal third of the forearm, maintaining the integrity of the arterial system, with its concomitant veins and motor branches of the median and ulnar nerves, leaving the skin envelope. In the recipient, the OMTS was removed, taking care to preserve the cutaneous cover with the digital arteries in continuity with the superficial palmar arch and radial and ulnar arteries. Also, the digital nerves were maintained in the skin flap, in continuity with the median and ulnar nerves. Their motor branches were divided after emergence from the main nerves. The superficial dorsal veins and radial nerve were kept adhered to the cutaneous cover. Then, the donor OMTS was placed within the recipient cutaneous flap; all the anatomic structures were repaired. The average surgical time was 780 minutes. Methylene blue was present in the digital arteries. There were no difficulties in the anatomic repair. The surgical technique is quite laborious, especially the dissection of the recipient interdigital spaces. Due to the requirement for arterial system integrity, the cutaneous flap must be viable. Also, the allotransplanted OMTS has all necessary conditions to obtain good tissue perfusion for subsequent function. Procurement without skin permits a greater opportunity to find donors, and greater social and personal acceptance by the recipient.
(Copyright 2010 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE