[Computer modeling of interaction of calix[4]arene C-99 with subfragment-1 of myometrium myosin].

Autor: Bevza OV, Bevza AA, Labyntseva RD, Cherenok SO, Kal'chenko VI, Kosterin SO
Jazyk: ukrajinština
Zdroj: Ukrains'kyi biokhimichnyi zhurnal (1999 ) [Ukr Biokhim Zh (1999)] 2010 Mar-Apr; Vol. 82 (2), pp. 85-93.
Abstrakt: In this work the computer design of interaction of calix[4]aren C-99 with a substrate-binding center of a functionally active area of a subfragment-1 myosin of the myometrium is carried out. It is shown when using methodology of molecular docking the receipt of ligand-receptor complexes which have geometry concerted with experimental data is possible. The cross-coupling of ATP and calix[4]aren C-99 on their orientation in ligand-binding center of subfragment-1 myosin of myometrium has been studied.
Databáze: MEDLINE