Predictive factors of non-deterioration of glucose tolerance following a 2-year behavioral intervention.
| Autor: | Almeida-Pititto B; Department of Nutrition, School of Public Health, University of Sao Paulo-Av, Dr, Arnaldo, 715, CEP 01246-904, São Paulo-SP, Brazil. sandrafv@usp.br., Hirai AT, Sartorelli DS, Harima HA, Gimeno SG, Ferreira SR |
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| Jazyk: | angličtina |
| Zdroj: | Diabetology & metabolic syndrome [Diabetol Metab Syndr] 2010 Jul 30; Vol. 2, pp. 52. Date of Electronic Publication: 2010 Jul 30. |
| DOI: | 10.1186/1758-5996-2-52 |
| Abstrakt: | Aim: To identify predictive factors associated with non-deterioration of glucose metabolism following a 2-year behavioral intervention in Japanese-Brazilians. Methods: 295 adults (59.7% women) without diabetes completed 2-year intervention program. Characteristics of those who maintained/improved glucose tolerance status (non-progressors) were compared with those who worsened (progressors) after the intervention. In logistic regression analysis, the condition of non-progressor was used as dependent variable. Results: Baseline characteristics of non-progressors (71.7%) and progressors were similar, except for the former being younger and having higher frequency of disturbed glucose tolerance and lower C-reactive protein (CRP). In logistic regression, non-deterioration of glucose metabolism was associated with disturbed glucose tolerance - impaired fasting glucose or impaired glucose tolerance - (p < 0.001) and CRP levels Conclusion: The whole sample presented a homogeneous behavior during the intervention. Lower CRP levels and diagnosis of glucose intolerance at baseline were predictors of non-deterioration of the glucose metabolism after a relatively simple intervention, independent of body adiposity. |
| Databáze: | MEDLINE |
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