Colorectal carcinoma: an update of current trends in Accra.
| Autor: | Dakubo JC; Department of Surgery, University of Ghana Medical School, Accra, Ghana. jdakubo@yahoo.com, Naaeder SB, Tettey Y, Gyasi RK |
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| Jazyk: | angličtina |
| Zdroj: | West African journal of medicine [West Afr J Med] 2010 May-Jun; Vol. 29 (3), pp. 178-83. |
| DOI: | 10.4314/wajm.v29i3.68218 |
| Abstrakt: | Background: Clinical experience and earlier studies indicate that the number of colorectal cancer cases seen annually in the Accra metropolis is increasing. Objective: This study was aimed at providing a current update on colorectal cancer in Accra, Ghana. Methods: A prospective study of confirmed cases of colorectal cancer diagnosed from January 1997- December 2007. Results: Three hundred and fifty-nine colorectal cancer cases were studied. Males were 192(53.5%) and females 167(46.5%) with an annual incidence of 32.6 new cases. The crude incidence rates were 12.53, 9.87 and 11.18 per 100,000 population for males, females and overall respectively. Rectal bleeding 185(51.1%), abdominal mass 76(21.1%), intestinal obstruction 62(17.3%), intestinal perforation nine (2.5%) and iron deficiency anaemia nine (2.5%) cases were the main presentations. There were 168 (46.8%) rectal and 191(53.2%) colon tumours. Two hundred and thirty-one patients had laparotomy with 225 resections, and 128 patients for various reasons did not undergo surgery. The Astler Coller stages of the tumours at diagnosis were C2 84(36.7%), C1 53(22.1%), B2 49(21.4%), D 17(7.4%), B1 14(6.1%) and A 12(5.1%) cases. Adenocarcinoma was the commonest histological type 321(89.4%), with the majority either well-differentiated (62.5%) or moderately well-differentiated (25.6) carcinomas. Poorly differentiated carcinomas accounted for 28 cases (7.8%). Post-operative mortality was 6.1%. Long term survival could not be assessed as the majority of patients were lost to follow up. Conclusion: The incidence of colorectal cancer has increased over the last four decades in tandem with an aging population of Accra with adenocarcinoma as the predominant histological type. |
| Databáze: | MEDLINE |
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