[The immunological indices of patients with chronic myeloleukemia at the blast crisis stage].

Autor: Romanova AF, Fedorovskaia EA, Pesotskaia LA
Jazyk: ruština
Zdroj: Vrachebnoe delo [Vrach Delo] 1991 Apr (4), pp. 65-7.
Abstrakt: Twenty patients with chronic myeloleucosis in the stage of blast crisis were examined. Results of immunological investigations indicate that these patients showed below normal indices of the absorptive and bactericidal function of polymorphous-nuclear neutrophils and cationic proteins. The number of T- and B-lymphocytes was also reduced. The immunity values were to the same degree inhibited as in patients with acute leucosis. Changes of the immune status depend on the degree of blastemia. Along with cytostatic agents patients with chronic myeloleucosis in the stage of blast crisis should undergo immunocorrection, primarily correction of cellular immunity.
Databáze: MEDLINE