Genetic variability of 15 autosomal STR loci in Russian populations.

Autor: Stepanov VA; Institute for Medical Genetics, Russian Academy of Medical Sciences, Nab. Ushayky 10, 634050, Tomsk, Russia. vadim.stepanov@medgenetics.ru, Melnikov AV, Lash-Zavada AY, Kharkov VN, Borinskaya SA, Tyazhelova TV, Zhukova OV, Schneider YV, Shil'nikova IN, Puzyrev VP, Rybakova AA, Yankovsky NK
Jazyk: angličtina
Zdroj: Legal medicine (Tokyo, Japan) [Leg Med (Tokyo)] 2010 Sep; Vol. 12 (5), pp. 256-8. Date of Electronic Publication: 2010 Jul 13.
DOI: 10.1016/j.legalmed.2010.05.006
Abstrakt: Allele frequencies for 15 STRs (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, THO1, TPOX, and vWA) in the PowerPlex 16 System (Promega Corporation) were assessed in 386 individuals from five Russian urban populations. No significant between-population differences in frequencies and molecular variance of 15 microsatellites were revealed. For all 15 loci, the combined matching probability is 3.19 x 10(-18) and the power of exclusion is 99.99989%.
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Databáze: MEDLINE