| Autor: |
Hileman CO; University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, Ohio 44106, USA., Carman TL, Gripshover BM, O'Riordan M, Storer NJ, Harrill DE, White CA, McComsey GA |
| Jazyk: |
angličtina |
| Zdroj: |
AIDS (London, England) [AIDS] 2010 Jul 31; Vol. 24 (12), pp. 1958-61. |
| DOI: |
10.1097/QAD.0b013e32833c3251 |
| Abstrakt: |
In this 13-week, open-label, randomized study of the anti-inflammatory salsalate versus usual care, there were no significant improvements in flow-mediated dilation of the brachial artery, endothelial activation, inflammation or coagulation markers, homeostasis model assessment of insulin resistance or lipoproteins with salsalate or between groups in virologically suppressed, HIV-infected adults on antiretrovirals. Tinnitus and transaminitis occurred frequently in the salsalate group. Dose reduction due to toxicities encountered and low level of inflammation may explain these results. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
