Evidences of osteoporosis improvement in Wistar rats treated with Ginkgo biloba extract: a histomorphometric study of mandible and femur.

Autor: Lucinda LM; Centro de Biologia da Reprodução, Federal University of Juiz de Fora, Caixa Postal 328, Zip Code 36001-970 Juiz de Fora, MG, Brazil. ledamarilia@yahoo.com.br, Vieira BJ, Oliveira TT, Sá RC, Peters VM, Reis JE, Guerra MO
Jazyk: angličtina
Zdroj: Fitoterapia [Fitoterapia] 2010 Dec; Vol. 81 (8), pp. 982-7. Date of Electronic Publication: 2010 Jun 25.
DOI: 10.1016/j.fitote.2010.06.014
Abstrakt: This study was aimed at investigating the anti-osteoporotic effects of the extract of Ginkgo biloba (EGb) in glucocorticoid-induced-osteoporosis. A significant reduction was observed in the percentage of the bone of the osteoporosis group in both the mandible and femur. The EGb group treated with 28 and 56 mg/Kg showed a significant increase in the percentage of trabecular bone (PTB) of the femur. The percentage of the alveolar bone of the mandible (PAB) had a significant increase with all doses of EGb. The treatment with EGb significantly reversed the loss of the PAB of the mandible and of the PTB of the femur.
(Copyright © 2010 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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