Effects of the continuous positive airway pressure on the airways of patients with chronic heart failure.

Autor:	Azevedo JC; Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil., Carvalho ER, Feijó LA, Oliveira FP, Menezes SL, Murad H
Jazyk:	English; Portuguese
Zdroj:	Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2010 Jul; Vol. 95 (1), pp. 115-21. Date of Electronic Publication: 2010 Jun 11.
DOI:	10.1590/s0066-782x2010005000068
Abstrakt:	Background: Heart failure can present with asymptomatic dysfunction at decompensation, with limitations and decrease in the productive capacity. The Continuous Positive Airway Pressure (CPAP) is a non-pharmacological means to decrease afterload. Objective: To analyze the effects of CPAP (10 cmH2O), for 30 days in patients with chronic heart failure. Methods: We assessed 10 patients with heart failure (6 males, 4 females) of several etiologies, with a mean age of 54 +/- 14 years, with a BMI of 21 +/- 0.04 kg/m(2). The therapy was applied for 60 min., 5 times a week for 30 days, during the daytime. The echocardiogram and the ergospirometry were analyzed, before and 30 days after the therapy. Results: There was a 19.59% increase in the left ventricular ejection fraction (LVEF): 23.9 +/- 8.91 vs 27.65 +/- 9.56%; p = 0.045. At the ergospirometry, the exercise time (ET) showed a significant increase from 547 +/- 151.319 vs 700 +/- 293.990 sec., p = 0.02; oxygen consumption (VO2) was 9.59 +/- 6.1 vs 4.51 +/- 2.67 ml x kg(-1) x min(-1), p = 0.01, whereas the carbon dioxide production (VCO2) at rest (9.85 +/- 4.38 vs 6.44 +/- 2.88 ml x kg(-1) x min(-1), p = 0.03) decreased. Conclusion: The CPAP resulted in an increase in the LVEF and ET, decreased the oxygen consumption and the carbon dioxide production at rest.
Databáze:	MEDLINE
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