Adipose tissue-derived stem cells: the friendly side of a classic cardiovascular foe.

Autor: Sanz-Ruiz R; Cardiology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Santos ME, Muñoa MD, Martín IL, Parma R, Fernández PL, Fernández-Avilés F
Jazyk: angličtina
Zdroj: Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2008 Mar; Vol. 1 (1), pp. 55-63. Date of Electronic Publication: 2008 Jan 29.
DOI: 10.1007/s12265-007-9006-9
Abstrakt: Recently, the existence of a population of stem cells located in the adipose tissue has been observed. Adipose-derived stem cells are able to differentiate into multiple cell lineages including cardiac myocytes. Hence, adipose-derived cells are emerging as a new source of adult stem cells for cardiovascular repair. In this review, we discuss the basic principles of adipose-derived stem cells (types and characteristics, obtention processes, immunophenotypic characterization, and cell potency), the initial experimental studies, and the currently ongoing clinical trials.
Databáze: MEDLINE