| Autor: |
Kensey KR; Kensey Nash Corporation, Exton, PA 19341., Michels M, Abrahams C, Nash JE, Miller FJ, Nash JC |
| Jazyk: |
angličtina |
| Zdroj: |
Investigative radiology [Invest Radiol] 1991 May; Vol. 26 (5), pp. 454-60. |
| Abstrakt: |
The authors describe here a rotary catheter for the percutaneous fragmentation of gallstones. Gallstones are drawn into the rotating impeller by a powerful vortex and mechanically fragmented. Fragments are aspirated from the gallbladder following use of the device. The safety and efficacy of the device was tested after placement of human gallstones in the pig's gallbladder in 19 acute, 15 chronic, and two control experiments. In 27 completed experiments, 206 human gallstones (6-20 mm) were implanted. Most residual fragments were less than 2 mm; 24 fragments were 2 to 4 mm and seven were 5 to 8 mm. Acute histologic changes included focal loss of mucosa, mucosal and submucosal hemorrhage, and deposition of biliary material in the mucosa and submucosa. At 30 and 90 days, gallbladder histology revealed regeneration of the mucosa with isolated granuloma formation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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