Cutaneous Mycobacterium haemophilum infection in a kidney transplant recipient after acupuncture treatment.

Autor: Castro-Silva AN; Laboratory of Cellular, Genetic and Molecular Nephrology, University of São Paulo, São Paulo, Brazil., Freire AO, Grinbaum RS, Elmor de Araújo MR, Abensur H, Araújo MR, Romão JE Jr, Sampaio JL, Noronha IL
Jazyk: angličtina
Zdroj: Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2011 Feb; Vol. 13 (1), pp. 33-7.
DOI: 10.1111/j.1399-3062.2010.00522.x
Abstrakt: Mycobacterium haemophilum is a slow-growing nontuberculous mycobacterium that can cause disease in both immunocompetent and immunocompromised patients. The most common clinical presentations of infection are the appearance of suppurative and ulcerated skin nodules. For the diagnosis, samples collected from suspected cases must be processed under the appropriate conditions, because M. haemophilum requires lower incubation temperatures and iron supplementation in order to grow in culture. In this case report, we describe the occurrence of skin lesions in a kidney transplant recipient, caused by M. haemophilum, associated with acupuncture treatment. The diagnosis was established by direct smear and culture of material aspirated from cutaneous lesions. Species identification was achieved by characterization of the growth requirements and by partial sequencing of the hsp65 gene. The patient was successfully treated with clarithromycin and ciprofloxacin for 12 months. Considering that the number of patients receiving acupuncture treatment is widely increasing, the implications of this potential complication should be recognized, particularly in immunosuppressed patients.
(© 2010 John Wiley & Sons A/S.)
Databáze: MEDLINE