High performance pathology workstation using an automated multispectral microscope.

Autor: Kasdan HL, Langford KC, Liberty J, Zachariash M, Deindoerfer FH
Jazyk: angličtina
Zdroj: Applied optics [Appl Opt] 1987 Aug 15; Vol. 26 (16), pp. 3294-300.
DOI: 10.1364/AO.26.003294
Abstrakt: Modern evaluation of cytological and histological specimens utilizes multispectral microscopic observation of transmissively illuminated fields as well as fluorescence images to analyze specimens treated with cytochemical probes. A user-friendly, interactive, multispectral image-processing capability is, therefore, required to accommodate the needs of the practicing cytologist. This paper describes a system design for a high-speed, microscopic, multispectral image analysis that provides a natural user-friendly environment for the cytologist. The speed limitations of conventional image processors are overcome by employing multiple processors in a high-speed, highly parallel-pipelined architecture. Preliminary results obtained using a prototype system for interactive ploidy determination will be presented. Software now under development will address a broad range of quantitative cytology problems utilizing the system's capability to measure a wide variety of cytomorphic properties in apparent real time.
Databáze: MEDLINE