| Autor: |
Lopes LC; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA., Guimarães AJ, de Cerqueira MD, Gómez BL, Nosanchuk JD |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2010 Jul; Vol. 17 (7), pp. 1155-8. Date of Electronic Publication: 2010 May 19. |
| DOI: |
10.1128/CVI.00033-10 |
| Abstrakt: |
Monoclonal antibodies to Histoplasma capsulatum can modify pathogenesis. We now show that monoclonal antibody H1C to a 70-kDa antigen increases intracellular fungal growth and reduces macrophage nitric oxide release but has no effect on fungal burden or survival in murine infection. This further demonstrates the complexities of host-pathogen interactions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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