Autor: |
Barra M; Clermont Université, Université Blaise Pascal, Laboratoire SEESIB, BP 10448, F-63000, Clermont-Ferrand, France., Roy O, Traïkia M, Taillefumier C |
Jazyk: |
angličtina |
Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2010 Jun 28; Vol. 8 (13), pp. 2941-55. Date of Electronic Publication: 2010 May 04. |
DOI: |
10.1039/b923275c |
Abstrakt: |
Azide- and alkynyl-containing homo-beta(3)-peptides, of up to six residues in length, were synthesised in solution from aspartic acid. Their subsequent conjugation with monosaccharides bearing an azide or a terminal alkyne function was efficiently achieved by copper-mediated cycloadditions leading to two novel families of small glycoclusters. These compounds represent ideal tools to explore carbohydrate-mediated multivalent interactions. |
Databáze: |
MEDLINE |
Externí odkaz: |
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