Oxygen-independent photonuclease activity of a new iron(II) complex.

Autor: de Souza B; Departamento de Química, Universidade Federal de Santa Catarina, 88040-900, Florianópolis, SC, Brazil., Xavier FR, Peralta RA, Bortoluzzi AJ, Conte G, Gallardo H, Fischer FL, Bussi G, Terenzi H, Neves A
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2010 May 21; Vol. 46 (19), pp. 3375-7. Date of Electronic Publication: 2010 Mar 18.
DOI: 10.1039/b922560a
Abstrakt: A new iron(ii) complex was synthesized and its photonuclease activity against plasmid DNA was evaluated. After kinetic experiments a k(cat) of 18.86 +/- 2.9 h(-1) was obtained, one of the highest nuclease activities of synthetic metallonucleases, selectively activated by 365 nm UV light.
Databáze: MEDLINE