Risk factors for colorrectal polyps in a Mexican population.

Autor:	González-González JA; Facultad de Medicina y Centro Regional para el Estudio de Enfermedades Digestivas (CREED), Hospital Universitario Dr. José Eleuterio González, UANL. Monterrey, NL. joseagonz@yahoo.com, Maldonado-Garza HJ, Flores-Rendón R, Garza-Galindo AA
Jazyk:	angličtina
Zdroj:	Revista de gastroenterologia de Mexico [Rev Gastroenterol Mex] 2009 Oct-Dec; Vol. 74 (4), pp. 295-300.
Abstrakt:	Background: The prevalence of colorectal polyps and adenomas in the general population of Mexico is unknown. Aim: To determine the prevalence and risk factors for colorectal polyps detected during flexible sigmoidoscopy (FSIG) in asymptomatic patients. Material and Methods: From 1995 to 2008, FSIG was performed as part of a complete check-up in patients who had lived in northeast Mexico for over 5 years. Results: 946 (794 males/152 females) were included in the study. The mean age was 48.8 years (range 21-91). A family history of colorectal cancer (FHCRC) was present in 2.2 % of the cases. The adenoma prevalence found in patients with a BMI < 25, 26-30 or > 30 was 7.3%, 6.2% and 10.2% respectively. Independent risk factor for colorrectal polyps and adenomas included a positive family history of colorrectal cancer (OR 12.4, 95% CI 19.1-230, and OR 12.4, 95% CI 4.1-37.3, respectively) and a body mass index < 25 (OR 4.2, 95% CI 4.2-14.2 and OR 4.2, 95% CI 1.8-9.7, respectively). Seventy two patients had polyps (7.6%) and 29 patients had adenomas (3%). The prevalence of polyps and adenomas on FSIG in patients younger than 50 years was 5.8% and 1.9% respectively, and among those older than 50 years, it was 8.9% and 4.8% respectively. Conclusion: A positive family history of colorectal cancer and a body mass index < 25 are independent risk factors for colorectal polyps and adenomas. The adenoma prevalence found in our population was lower than the reported in developed countries.
Databáze:	MEDLINE
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