| Autor: |
Osawa A; Department of Food and Nutrition, Japan Women's University, Mejirodai, Bunkyo-ku, Tokyo, Japan., Ishii Y, Sasamura N, Morita M, Köcher S, Müller V, Sandmann G, Shindo K |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of antibiotics [J Antibiot (Tokyo)] 2010 Jun; Vol. 63 (6), pp. 291-5. Date of Electronic Publication: 2010 Apr 23. |
| DOI: |
10.1038/ja.2010.33 |
| Abstrakt: |
We performed the chemical mutagenesis of Halobacillus halophilus (the producer of a C(30) carotenoid, methyl glucosyl-3,4-dehydro-apo-8'-lycopenoate) to isolate novel carotenoids that are biosynthetic intermediates of methyl glucosyl-3,4-dehydro-apo-8'-lycopenoate. As a result, we isolated two novel C(30) carotenoids, hydroxy-3,4-dehydro-apo-8'-lycopene and methyl hydroxy-3,4-dehydro-apo-8'-lycopenoate, which were biosynthesized through a novel 8'-apo C(30) pathway. These carotenoids showed antioxidative activity in the (1)O(2) suppression model. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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