Natural occurrence of horizontal transfer of Mycobacterium avium- specific insertion sequence IS1245 to Mycobacterium kansasii.

Autor: da Silva Rabello MC; Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Sao Paulo, Rua Botucatu, 862 3 degrees Andar, 04023-062 Sao Paulo, SP, Brazil., de Oliveira RS, Silva RM, Leao SC
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2010 Jun; Vol. 48 (6), pp. 2257-9. Date of Electronic Publication: 2010 Apr 14.
DOI: 10.1128/JCM.02256-09
Abstrakt: Mycobacterium kansasii carrying IS1245, a highly prevalent insertion sequence among Mycobacterium avium isolates, was detected in a mixed culture of M. avium and M. kansasii. The insertion sequence was stable and able to transpose by a replicative mechanism in M. kansasii. These findings may have significant implications for molecular diagnosis and treatment outcome.
Databáze: MEDLINE