[Protective and reactivating effect of the protein exometabolite on yeast cells inactivated by the ultraviolet irradiation].

Autor: Vorob'eva LI, Khodzhaev EIu
Jazyk: ruština
Zdroj: Prikladnaia biokhimiia i mikrobiologiia [Prikl Biokhim Mikrobiol] 2010 Mar-Apr; Vol. 46 (2), pp. 191-7.
Abstrakt: It has been shown that Saccharomyces cerevisiae, Kluyveromyces lactis, and Candida utilis strains produce the protein exometabolites, which has a protective and reactivating effect on the ultraviolet irradiated yeast cells. The protective effect of the preliminary ultraviolet irradiated (activated) protein exometabolite of all strains increased 2-3 times, though its reactivating activity did not change. Yarrowia lipolytica yeast cells, isolated from the areas with the high daily irradiation, and Endomyces magnusii, the obligate fungi parasites, were characterized by the highest ultraviolet tolerance in comparison with the other strains. However, they did not produce the exometabolites with the antistress effect. Luteococcus casei reactivating factor demonstrated protective and reactivating cross-action in relation to the ultraviolet irradiated S. cerevisiae, K. lactis, and C. utilis cells and were inactive in relation to Y. lipolytica and E. magnusii. Using killer and nonkiller S. cerevisiae strain, it has been shown that the peptide exometabolite accumulation was not associated with toxin production.
Databáze: MEDLINE