[Proliferation markers used in histological studies].
| Autor: | Kirik OV, Beznin GV, Korzhevskiĭ DE |
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| Jazyk: | ruština |
| Zdroj: | Morfologiia (Saint Petersburg, Russia) [Morfologiia] 2009; Vol. 136 (6), pp. 95-100. |
| Abstrakt: | The present paper reviews the current approaches used to study cell proliferative activity. In the last years, a number of proteins involved in cell cycle control were discovered, that may serve as selective markers of proliferating cells. This work gives the characteristics of immunocytochemical methods demonstrating 5-bromodeoxyuridine, PCNA, Ki-67, FEN-1, phosphorylated histone H3 and cyclins. The data on the role of these proteins in cell cycle control are presented. |
| Databáze: | MEDLINE |
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