Clinico-pathologic patterns of extremity liposarcoma.
| Autor: | Eyesan SU; Department of Orthopaedics and Trauma Surgery, National Orthopaedic Hospital, Lagos., Obalum DC, Onovo DO, Ketiku KK, Abdulkareem FB |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | The Nigerian postgraduate medical journal [Niger Postgrad Med J] 2010 Mar; Vol. 17 (1), pp. 27-9. |
| Abstrakt: | Background: Liposarcoma is a tumour derived from primitive cells that undergo adipose differentiation. Objective: To describe the clinico-pathological pattern of extremity liposarcoma in Lagos, Nigeria. Methods: This is a descriptive study of patients with histologically established liposarcoma affecting the extremities seen at the Oncology unit of the National Orthopaedic Hospital, Lagos Nigeria. Demographic and clinical data ( including age, gender, presenting complaints anatomic location of lesions ), histologic type, clinical stage and treatment outcome were collected using a prepared proforma and analysed. Results: Liposarcoma accounted for 6 [27.3%] of 22 cases of soft tissue sarcomas seen within the study period. All 6 were males with a M:F of 6:0. The age range was 36- 59 years. Lesions were mostly located in the thigh 5/6 (83.3%). The most common histologic type was myxoid seen in 3/6 [50%]. All presented at stage T2bNoMo. Five (83.3%) had limb salvage surgery with adjuvant radiotherapy while one had ablative surgery. Survival and recurrent rates could not be determined as all patients were lost to follow-up soon after surgery. Conclusion: Liposarcoma is the commonest extremity soft tissue sarcoma seen in our centre, the myxoid type being the commonest histologic subtype. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|