Survey of natural infection by Leishmania in sand fly species collected in southeastern Brazil.
| Autor: | Rocha LS; Laboratório de Pesquisa em Leishmaniose, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brasil., Falqueto A, dos Santos CB, Ferreira AL, da Graça GC, Grimaldi G Jr, Cupolillo E |
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| Jazyk: | angličtina |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2010 Jul; Vol. 104 (7), pp. 461-6. Date of Electronic Publication: 2010 Mar 26. |
| DOI: | 10.1016/j.trstmh.2010.02.005 |
| Abstrakt: | In this study, we sought to identify sand fly vectors of the Leishmania species that circulate in distinct eco-epidemiological disease-endemic rural areas within the Espírito Santo State in southeastern Brazil. PCR amplification of a conserved region of the minicircle kDNA was used to estimate infection rates in field-captured, peridomestic female sand flies. Only 13 of the 1689 female sand fly specimens (0.77%) actually contained Leishmania DNA. Leishmania braziliensis infections were found in Lutzomyia intermedia and Lu. whitmani, and, for the first time, in Lu. fischeri and Lu. ferreirana. Interestingly, the high rate of genetic polymorphism of the L. braziliensis parasites in one of the disease-endemic areas that were studied may reflect specific transmission cycles involving different sand fly vectors. (Copyright 2010 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
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