Autor: |
Sergeev PV, Bol'shev VN, Khalilov EM |
Jazyk: |
ruština |
Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1977 Jul-Aug; Vol. 40 (4), pp. 445-7. |
Abstrakt: |
The effect of roentgen-contrast media on the activity of the NADP'N and NAD'N-dependent electron-transport chains of the rats liver microsomes was studied. Bilignost, cardiotrast, triiotrast and triombrin are shown to lower the rate of the NADP'N oxidation by the rats' liver microsomes and have no effect (except for triiotrast) upon the rate of the NAD'N oxidation. It is presumed that the relative resistance of the NAD'N-specific flavoproteid is due to the presence of a hydrophobic layer impervious to the polar molecules of the contrast media. |
Databáze: |
MEDLINE |
Externí odkaz: |
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