[Chronic inflammatory demyelinating polyneuropathy after treatment with pegylated interferon alpha 2b in a patient with HIV/HCV coinfection: case report].

Autor: Bassetti BR; Curso de Medicina, Escola Superior de Ciências, Santa Casa de Misericórdia de Vitória, ES., Trés ES, Ciríaco JG, Pinto Neto LF
Jazyk: portugalština
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2010 Jan-Feb; Vol. 43 (1), pp. 89-91.
DOI: 10.1590/s0037-86822010000100019
Abstrakt: Chronic inflammatory demyelinating polyneuropathy has a strong association with HIV and HCV infection. A rare association between chronic inflammatory demyelinating polyneuropathy and hepatitis C treatment with pegylated interferon alpha was described recently. We described the first case of chronic inflammatory demyelinating polyneuropathy associated with pegylated interferon alpha 2b in a white man infected with HIV and HCV. The patient recovered completely with the use of intravenous hyperimmune immunoglobulin. Infectologists and hepatologists should be alert regarding this rare and serious association, which requires immediately drug discontinuation and early treatment.
Databáze: MEDLINE