Risk factors for depression and anxiety in survivors of acute respiratory distress syndrome.

Autor: Hopkins RO; Pulmonary and Critical Care Division, Department of Medicine, LDS Hospital, Salt Lake City, UT 84107, USA. ramona.hopkins@imail.org, Key CW, Suchyta MR, Weaver LK, Orme JF Jr
Jazyk: angličtina
Zdroj: General hospital psychiatry [Gen Hosp Psychiatry] 2010 Mar-Apr; Vol. 32 (2), pp. 147-55. Date of Electronic Publication: 2009 Dec 14.
DOI: 10.1016/j.genhosppsych.2009.11.003
Abstrakt: Objective: Depression and anxiety are common morbidities of critical illness. We assessed risk factors of depression and anxiety in Acute Respiratory Distress Syndrome (ARDS) survivors at 1 and 2 years post-hospital discharge.
Method: Risk factors for depression and anxiety at 1 and 2 years were assessed using stepwise multiple regression analyses, with and without 1-year outcomes.
Results: ARDS survivors had depression (16% and 23%) and anxiety (24% and 23%) at 1 and 2 years, respectively. Predictors of depression at 1 year were alcohol dependence, female gender and younger age (P=.006). Predictors of anxiety were ratio of arterial oxygen tension to inspired oxygen fraction and duration of mechanical ventilation (P<.005). Predictors of depression at 2 years were depression at 1 year and the presence of cognitive sequelae (P<.0001). Predictors of anxiety at 2 years was anxiety at 1 year (P<.0001).
Conclusions: Medical variables that predicted depression or anxiety at 1 year no longer predicted depression and anxiety at 2 years. Medical variables appear to have a short-term effect on psychiatric outcomes. At 2 years lifestyle behaviors including history of smoking along with cognitive sequelae, depression and anxiety at 1 year predict depression and anxiety.
(Copyright 2010 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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