| Autor: |
England JM; Department of Pathology and Laboratory Medicine, Medical College of Pennsylvania, Philadelphia 19129., Panella MJ, Ewert DL, Halpern MS |
| Jazyk: |
angličtina |
| Zdroj: |
Virology [Virology] 1991 Jun; Vol. 182 (2), pp. 423-9. |
| DOI: |
10.1016/0042-6822(91)90583-w |
| Abstrakt: |
The presence of peritoneum-based, cytokeratin-positive tumor cells, as detected under conditions of intravenous inoculation of chickens with a v-src-positive DNA fragment, raised the possibility that such DNA may be inductive for diffuse mesothelioma. To investigate this possibility, chickens were inoculated intraperitoneally with v-src DNA, and the resultant peritoneum-based tumor tissue was subjected to histopathological analysis. On the basis of (i) morphology, (ii) immunohistochemistry/histochemistry, and (iii) ultrastructure, we concluded that this tissue represents a diffuse mesothelioma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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