[Neuronal plasticity and gene expression].

Autor: Sokolova OO, Shtark MB, Lisachev PD
Jazyk: ruština
Zdroj: Uspekhi fiziologicheskikh nauk [Usp Fiziol Nauk] 2010 Jan-Mar; Vol. 41 (1), pp. 26-44.
Abstrakt: Neuronal plasticity--a fundamental feature of brain--provides adequate interactions with dynamic environment. One of the most deeply investigated forms of the neuronal plasticity is a long-term potentiation (LTP)--a phenomenon underlying learning and memory. Signal paths activated during LTP converge into the nuclear of the neuron, giving rise to launch of the molecular-genetic programs, which mediate structural and functional remodeling of synapses. In the review data concerning involvement of multilevel gene expression into plastic change under neuronal activation are summarized.
Databáze: MEDLINE