| Autor: |
Moreira RC; Serviço de Virologia, Instituto Adolfo Lutz, São Paulo, SP, Brasil. regina.moreira7@gmail.com, Deguti MM, Lemos MF, Saraceni CP, Oba IT, Spina AM, Nascimento-Lima AS, Fares J, Azevedo RS, Gomes-Gouvêa MS, Carrilho FJ, Pinho JR |
| Jazyk: |
angličtina |
| Zdroj: |
Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2010 Feb; Vol. 105 (1), pp. 107-8. |
| DOI: |
10.1590/s0074-02762010000100017 |
| Abstrakt: |
The aim of this study was to determine the prevalence and the incidence of hepatitis B virus (HBV) among haemodialysis (HD) subjects and to evaluate whether testing for serological markers at the time of admission is suitable for HBV screening in this population. One hundred twenty-three patients belonging to two HD centres from São Paulo, Brazil, were tested prospectively. HBV DNA was detected by polymerase chain reaction (PCR) in each of the prospective subjects (n = 123) during one year. Additionally, all samples (n = 1,476) were analysed for HBV serological markers. The prevalence of hepatitis B core antibody (anti-HBc), hepatitis B surface antigen (HBsAg) and HBV DNA were 34.1%, 15.4% and 8.1%, respectively, while the incidence was null. Fluctuation in HBV serology was observed in one patient. Only 37.8% (17/45) of cases responded to the HBV vaccine. Our results suggest that employing more than one HBV marker and repeated follow-up evaluations may improve HBV screening in HD units. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
