| Autor: |
Lafayette TC; Department of Pediatric Hematology-Oncology, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil. tcslaf@terra.com.br, Coser VM, Brûlé AO, Coser PL, Pereira WV |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2010 Apr; Vol. 32 (3), pp. 229-32. |
| DOI: |
10.1097/MPH.0b013e3181cf7ef3 |
| Abstrakt: |
Extramedullary involvement occurs infrequently in acute promyelocytic leukemia and is said to be more common after treatment with all-trans retinoic acid. We describe a 9-year-old girl who had an isolated external auditory canal and middle ear relapse after treatment with all-trans retinoic acid and chemotherapy. A patient with cytogenetically and molecularly confirmed acute promyelocytic leukemia developed isolated extramedullary relapse in the auditory canal and middle ear 4 years and 9 months after initial diagnosis, while in hematologic and molecular remission, successfully treated with arsenic trioxide alone. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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