Autor: |
Pereira SM; Post-Graduate Department, Fernandes Figueira Institute, Rui Barbosa Avenue, 716, Flamengo, Rio de Janeiro 22250-020, Brazil., de Almeida Cardoso MH, Figuexeds AL, Mattos H, Rozembaum R, Ferreira VI, Portinho MA, Gonçalves AC, da Costa ES |
Jazyk: |
angličtina |
Zdroj: |
International journal of pediatrics [Int J Pediatr] 2009; Vol. 2009, pp. 427682. Date of Electronic Publication: 2010 Feb 21. |
DOI: |
10.1155/2009/427682 |
Abstrakt: |
The aim of this study is to identify risk factors for sepsis-related mortality in low birth weight (<1500 g) infants. We performed retrospective cohort study to investigate risk factors for sepsis-related mortality in all neonates birth weight <1500 g admitted to Level III neonatal intensive care unit, Brazil, April 2001/September 2004. Of the 203 cases, 71 (35%) had sepsis. Of those, gram-positive was identified in 52/87 blood cultures (59.8%), the most common Coagulase-negative Staphylococcus (31/87; 35.5%). Gram-negative was present in 29 of the 87 positive blood cultures (33.3%), with Pseudomonas aeruginosa (8/87; 9.1%), the most frequent agent. Overall 21 of 71 infants with sepsis (29.6%) died. Risk factors for sepsis-related mortality were gestational age =28 weeks, birth weight =1000 g (9.6 times more often than birth weight >1000 g), five-minute Apgar =7, gram-negative sepsis, mechanical ventilation (6.7 times higher than no use), and intravascular catheter. Sepsis-related mortality was due, mainly, to Pseudomonas aeruginosa; birth weight =1000 g and mechanical ventilation were strong sepsis-related mortality predictors. |
Databáze: |
MEDLINE |
Externí odkaz: |
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