Effect of hyperprolactinemia on pituitary-adrenal function.

Autor: Feldman JM, Plonk JW
Jazyk: angličtina
Zdroj: Hormone research [Horm Res] 1978; Vol. 9 (1), pp. 1-11.
DOI: 10.1159/000178891
Abstrakt: Three patients with hyperprolactinemia (2 with pituitary tumors and 1 with a hypothalamic disturbance) underwent evaluation of their hypothalamic-pituitary-adrenal axis using ACTH, metyrapone and in one case repetitive insulin tolerance tests. With the exception of a suggestion of a slight increase in adrenal responsiveness to pharmacological doses of ACTH in one of the patients, there was no alteration in the adrenal responsiveness of the 3 patients evaluated. We conclude that hyperprolactinemia probably does not systematically modify the responsiveness of the hypothalamic-pituitary-adrenal axis.
Databáze: MEDLINE