Efficient microwave-assisted synthesis of unsymmetrical disulfides.

Autor: Görmer K; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto Hahn Strasse 11, 44227 Dortmund, Germany., Waldmann H, Triola G
Jazyk: angličtina
Zdroj: The Journal of organic chemistry [J Org Chem] 2010 Mar 05; Vol. 75 (5), pp. 1811-3.
DOI: 10.1021/jo902695a
Abstrakt: An efficient synthesis of unsymmetrical disulfides exemplified for cysteines and penicillamines is described. The use of dimethyl sulfoxide mediated oxidation accelerated by microwave irradiation afforded various unsymmetrical disulfides in one step and in high yields.
Databáze: MEDLINE