| Autor: |
Lalloo UG; Department of Medicine, University of Natal, Durban., Cooper K, Irusen EM, le Roux BT, Jogessar VB |
| Jazyk: |
angličtina |
| Zdroj: |
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [S Afr Med J] 1991 Mar 02; Vol. 79 (5), pp. 274-8. |
| Abstrakt: |
Only 1 case of lymphomatoid granulomatosis has previously been reported from South Africa. Experience with 4 such adult patients (2 blacks and 2 whites) is described. These patients were followed up for 15-48 months and none developed evidence of a lymphoma during this period. Fever, weight loss, cough and breathlessness were prominent symptoms in all patients. One patient, a black woman, with a diffuse interstitial pattern of lung involvement, had digital clubbing--a rare accompaniment that resolved after therapy. Dilated congestive cardiomyopathy was found in association with pulmonary nodules in a black male patient. All 4 patients were treated with cytotoxic regimens. The 2 patients treated with oral cyclophosphamide and prednisolone responded favourably. The possible explanation for paucity of reports of lymphomatoid granulomatosis from South Africa could be under-reporting, underdiagnosis or a true geographic/ethnic variation in the incidence of this condition. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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