A case-control study of the risk factors associated with sinonasal inverted papilloma.
| Autor: | Sham CL; Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Lee DL, van Hasselt CA, Tong MC |
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| Jazyk: | angličtina |
| Zdroj: | American journal of rhinology & allergy [Am J Rhinol Allergy] 2010 Jan-Feb; Vol. 24 (1), pp. e37-40. |
| DOI: | 10.2500/ajra.2010.24.3408 |
| Abstrakt: | Background: The etiology of sinonasal inverted papilloma (IP) is unknown. This study was designed to evaluate the possible risk factors associated with IP Methods: This is a case-control epidemiology study in a tertiary referral center. Fifty patients with IP and 150 matched controls were interviewed using a questionnaire on suspected risk factors. Univariate analysis of the risk factors and calculation of the matched odds ratios, the corresponding 95% CIs, and p values was performed. Significant risk factors were further studied using conditional logistic regression analysis. Results: Outdoor and industrial occupations were associated with IP. Tobacco smoking, drinking alcohol, history of allergic rhinitis, sinusitis, nasal polyp, non-sinonasal papilloma and non-sinonasal malignancy were not significant factors. Conclusion: Outdoor and industrial occupations were associated with IP and may be potential risk factors. Future studies are warranted to further evaluate the individual type of occupation and chemical involved. |
| Databáze: | MEDLINE |
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