[Detection of human papillomavirus in esophageal carcinoma tissues from Baoding City of Hebei Province].
| Autor: | Zhao XY; College of Life Sciences, Hebei University, Baoding 071002, China., Li SY, Li Y, Wang XL, Li YL, Wu XZ, Zhou L, Liu HT, Zeng Y |
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| Jazyk: | čínština |
| Zdroj: | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi] 2009 Apr; Vol. 23 (2), pp. 91-3. |
| Abstrakt: | Objective: To investigate the relationship between the human papillomavirus (HPV) and esophageal carcinoma in Baoding City of Hebei Province. Methods: We detected HPV DNA in 42 formalin-fixed and paraffin-embedded tissues from surgically resected esophageal carcinomas from Baoding City of Hebei Province, by PCR with the general primer set of GP5 + /6 + for HPV L1 gene and type-specific primer sets for HPV16 and 18 as well. Results: 37 from 42 esophageal carcinoma samples were HPV positive and the rate was 88.1%. Among the samples detected, 19 were HPV16 E6 positive and rate was 45.2%, eight were HPV18 E6 positive and rate was 19.0%. Conclusion: The high rate of HPV in the esophageal carcinoma samples suggested that HPV plays an etiologic role in the development of esophageal cancer in Baoding City of Hebei Province. |
| Databáze: | MEDLINE |
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