[Hereditary tylosis syndrome and esophagus cancer].

Autor: de Souza CA; Faculdade de Medicina do Vale do Aço, Ipatinga, MG, Brasil. kkmedicina@yahoo.com.br, Santos Ada C, Santos Lda C, Carneiro AL
Jazyk: portugalština
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2009 Sep-Oct; Vol. 84 (5), pp. 527-9.
DOI: 10.1590/s0365-05962009000500014
Abstrakt: Tylosis palmoplantaris is an autosomal dominant disorder characterized by hyperkeratosis of palms and soles. Lesions start during childhood and are more evident in areas of pressure. Familial tylosis palmoplantaris comprises two forms: epidermolytic and non-epidermolytic. Patients with the epidermolytic variant have up to 40% higher chance of developing squamous cell carcinoma of the esophagus. The association of tylosis palmoplantaris with esophageal cancer is called Howel-Evans syndrome.
Databáze: MEDLINE