| Autor: |
Knight ZA; Zachary A. Knight is at The Rockefeller University, New York, New York 10065, USA., Lin H, Shokat KM |
| Jazyk: |
angličtina |
| Zdroj: |
Nature reviews. Cancer [Nat Rev Cancer] 2010 Feb; Vol. 10 (2), pp. 130-7. |
| DOI: |
10.1038/nrc2787 |
| Abstrakt: |
Kinase inhibitors are the largest class of new cancer drugs. However, it is already apparent that most tumours can escape from the inhibition of any single kinase. If it is necessary to inhibit multiple kinases, how do we choose which ones? In this Opinion article, we discuss some of the strategies that are currently being used to identify new therapeutic combinations of kinase targets. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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