Iodine intake is still inadequate among pregnant women eight years after mandatory iodination of salt in Turkey.

Autor: Kut A; Department of Family Medicine, Baskent University Faculty of Medicine, Ankara, Turkey., Gursoy A, Senbayram S, Bayraktar N, Budakoğlu II, Akgün HS
Jazyk: angličtina
Zdroj: Journal of endocrinological investigation [J Endocrinol Invest] 2010 Jul-Aug; Vol. 33 (7), pp. 461-4. Date of Electronic Publication: 2009 Dec 22.
DOI: 10.3275/6767
Abstrakt: Background: A recent study showed first sign of reduction in goiter prevalence and elimination of iodine deficiency state among school-age children in Turkey after a decade of mandatory iodination of table salt. However, iodine status among pregnant women is a still debated issue in our country.
Aim: To investigate iodine status, iodized salt consumption rate, and goiter prevalence in 1st trimester pregnant women 8 yr after the mandatory iodination. MATERIAL/ SUBJECTS AND METHODS: One hundred and forty-one 1sttrimester pregnant women who had been followed-up between January and October 2006 in the obstetric outpatient clinics in Turkey were included. Besides a physical examination, subjects underwent laboratory investigations for free T(3), free T(4), and urinary iodine concentration (UIC). All subjects completed a questionnaire regarding sociodemographic parameters, use of iodized salt, and pregnancy history. Goiter status was revealed by a palpation method according to World Health Organization (WHO) guidelines.
Results: In this study, we found that the median UIC of pregnant women was 149.7 microg/l (range 20.9-275.1 microg/l). Almost half of the subjects were below the WHO, United Nations Children's Fund, and International Council for the Control of Iodine Deficiency Disorders lower median reference limits of 150 microg/l. Total goiter prevalence was 24.8%, of which 9.2% were visible goiters. Among the study patients, 2.1% had subclinical hypothyroidism, and 0.7% had overt hypothyroidism. The rate for iodized salt use among the pregnant women was 95%.
Conclusion: Our study revealed that iodine deficiency still remains a serious problem for pregnant women. Based on our results, antenatal follow-up protocols in the primary care setting in Turkey must include iodine supplementation.
Databáze: MEDLINE
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