Autor: |
Manus LM; Department of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, USA., Mastarone DJ, Waters EA, Zhang XQ, Schultz-Sikma EA, Macrenaris KW, Ho D, Meade TJ |
Jazyk: |
angličtina |
Zdroj: |
Nano letters [Nano Lett] 2010 Feb 10; Vol. 10 (2), pp. 484-9. |
DOI: |
10.1021/nl903264h |
Abstrakt: |
A Gd(III)-nanodiamond conjugate [Gd(III)-ND] was prepared and characterized, enabling detection of nanodiamonds by MR imaging. The Gd(III)-ND particles significantly reduced the T(1) of water protons with a per-Gd(III) relaxivity of 58.82 +/- 1.18 mM(-1) s(-1) at 1.5 T (60 MHz). This represents a 10-fold increase compared to the monomer Gd(III) complex (r(1) = 5.42 +/- 0.20 mM(-1) s(-1)) and is among the highest per-Gd(III) relaxivities reported. |
Databáze: |
MEDLINE |
Externí odkaz: |
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